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Westward expansion was greatly aided in the early 19th century by the Louisiana Purchase (1803), which was followed by the Corps of Discovery Expedition that is generally called the Lewis and Clark Expedition; the War of 1812, which secured existing U. boundaries and defeated native tribes of the Old Northwest, the region of the Ohio and Upper Mississippi valleys; and the Indian Removal Act of 1830, which forcibly moved virtually all Indians from the Southeast to the present states of Arkansas and Oklahoma, a journey known as the Trail of Tears.